Disclaimer: This content is provided for informational purposes only and does not intend to substitute financial, educational, health, nutritional, medical, legal, etc advice provided by a professional.
The very low-calorie ketogenic diet (VLCKD) has gained popularity as an effective tool for weight loss in patients with obesity and mild kidney failure. Traditionally considered high protein, ketogenic diets were often viewed with concern by clinicians due to potential harm to kidney function. However, recent studies have evaluated the efficacy and safety of VLCKD and found it to be a safe and effective tool for weight loss.
A clinical trial published in the PubMed database evaluated the effectiveness and safety of VLCKD in patients with obesity and mild kidney failure. The study found that VLCKD led to significant weight loss and improved body composition parameters. Additionally, levels of high sensitivity C-reactive protein (hs-CRP) were significantly reduced, indicating a decrease in inflammation. Both systolic and diastolic blood pressure also showed significant improvements.
Further analysis of the study data revealed correlations between blood pressure and various anthropometric parameters such as body mass index (BMI), waist circumference, and fat mass. Changes in blood pressure were also associated with changes in BMI, hs-CRP levels, and body composition parameters. Multiple regression analysis identified hs-CRP levels as a significant predictor of changes in blood pressure.
The benefits of VLCKD extend beyond weight loss. VLCKD has been shown to preserve fatty free mass, which plays a crucial role in glucose metabolism. Rapid weight loss achieved through VLCKD can also lead to a positive psychological cycle, increasing compliance with the diet.
Despite the clinical evidence supporting the efficacy of VLCKD, there is a lack of data regarding its management. To address this gap, a practical guide was published in the Journal of Translational Medicine. The guide provides recommendations for the correct use of VLCKD for weight loss and management of side effects.
The very low-calorie ketogenic diet (VLCKD) is a safe and effective tool for weight loss in patients with obesity and mild kidney failure. It leads to significant improvements in body composition parameters, blood pressure, and inflammation levels. VLCKD also offers additional benefits such as the preservation of fatty free mass and increased compliance with the diet. With proper management, VLCKD can be a valuable nutritional approach for individuals seeking to lose weight and improve their overall health.
Disclaimer: This content is provided for informational purposes only and does not intend to substitute financial, educational, health, nutritional, medical, legal, etc advice provided by a professional.